









Power through your pain with Vicks PainQuil and PainQuil PM adult liquid pain relievers! For pain relief anytime, PainQuil starts working fast for relief of headaches, sore throat, minor aches & pains. For pain relief at night, PainQuil PM starts work fast for relief of sleeplessness + headaches, sore throat, minor aches & pains. PainQuil and PainQuil PM deliver max strength‡ pain relief with 1000mg Acetaminophen per dose for pain relief. PainQuil PM also delivers 50mg diphenhydramine HCl per dose to help you sleep soundly. These adult pain relief liquids are deliciously flavored; PainQuil is black cherry flavored, and PainQuil PM is midnight cherry flavored. Both PainQuil and PainQuil PM are non-habit forming. They are also free of high fructose corn syrup and free of sugar. PainQuil and PainQuil PM are from the makers of Vicks, with over 125 years of health care expertise. ‡Maximum strength dose of active ingredients per dosing interval, only use as directed.
Product Dimensions : 5.47 x 2.2 x 7.4 inches; 1.96 Pounds
Date First Available : March 25, 2025
Manufacturer : Procter & Gamble
ASIN : B0DSGHNH8M
Best Sellers Rank: #6,049 in Health & Household (See Top 100 in Health & Household) #33 in Acetaminophen
Customer Reviews: 4.5 4.5 out of 5 stars 1,593 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
MAX STRENGTH PAIN RELIEVERS: Use PainQuil for max strength pain relief (1000mg Acetaminophen) for pain relief anytime. At night, use PainQuil PM for max strength nighttime pain relief, with 1000mg Acetaminophen and 50mg DPH per dose.
STARTS WORKING FAST: PainQuil & PainQuil PM start working fast for relief of headaches, sore throat, minor aches & pains. PainQuil PM relieves sleeplessness + headaches, sore throat, minor aches & pains, so sleep soundly.
LIQUID PAIN RELIEF: PainQuil and PainQuil PM offer max strength pain relief in a soothing liquid.
GREAT TASTE: These adult pain relief liquids are deliciously flavored; PainQuil is black cherry flavored, and PainQuil PM is midnight cherry flavored.
NON-HABIT FORMING: both PainQuil and PainQuil PM are non-habit forming. They are also free of sugar and free of high fructose corn syrup.
FROM THE MAKERS OF VICKS: All PainQuil products are specifically formulated by our team of dedicated scientists, with over 125 years of health care expertise.
8 reviews for Vicks PainQuil & PainQuil PM Pain Relief Liquid, 1000mg Acetaminophen, 2×12 oz
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$14.97

✨️Makeup Skincare and Fragrance Lover ✨️ –
Helps with pain, and the PM version really helps with sleep.
I had never seen this product before; however, while searching for pain relievers, these ‘Vicks’ PainQuil & PainQuil PM pain relief liquid came up. I decided to give this set a try, and wow am I glad I did!This set comes with a bottle for the daytime, and one for night (hence, the PM). These are each 12 oz bottles, and so I feel they’ll last me a while. I like that these contain acetaminophen in them, but in liquid form. For me, it seems like this liquid starts working within a short amount of time (like 5 or 10 minutes).Each dose is 30 mL (for both bottles), and each dose contains 1000mg of acetaminophen (with the night-time version also containing 50mg of diphenhydramine HCI). There are dosing cups included with each bottle, so that I can know I’m using the correct amount.I can feel relief of aches and pains quickly after using; it really is such a powerful pain reliever for me. Also, the night-time version not only helps me with aches and pains; additionally helps with the sleeplessness and restlessness, sending me off to a peaceful slumber.These liquids do work wonderfully for me and my needs. The taste is a little strong, but it’s not too bad. I’d gladly put up with the taste, for the amount of relief I receive from these products. I think this is a nice value for both of the bottles. I highly recommend this to my family and friends, as it works so nicely. I’m very pleased with this product.
CatOrtiz –
Best over the counter pain medicine!
Used this when I had my tonsils removed and it worked wonderfully! Hubby used it after knee surgery and loved it also.
Judy Richardson –
Pain quil by Vicks
This medicine worked really good for me. And the pain quil p.m.. really helped me sleep even with the pain. I have bought some also for my daughter who has a bad back and she said it helped her a lot.
kelvin Hughes –
Good product
This product helps with pain relief and discomfort as well as the addition of the pain sleep aid. The taste is a bit strong but the pain relief is what you’re looking for.
Patricia Gordon –
this stuff really works!
I bought this product sort of out of desperation; let me explain: I have an auto immune disease called Sjögen’s Syndrome. one of the effects of this disorder is extreme dry mouth. i take medication for this, but it doesn’t work 100%. so, my mouth gets very dry and i get ulcers on the side of my tongue. because of nerve placement, the pain radiates to my teeth and gums, my jawbone, and causes pain deep inside my ear. i am on narcotic pain meds for other conditions, but nothing even TOUCHES the mouth pain. Until i discovered PainQuil. anyone who has ever had a toothache knows that that is some of the most intense pain you can experience, it is so painful that you cannot ignore it. but the PainQuil kills that pain IMMEDIATELY. no exaggeration. the only drawback i felt was that the PM version had me a bit groggy when i woke up the next morning. Other than that, this is the real thing. i can not recommend it enough.
Brandon Krupka –
Helps with sleep and pain
Wasn’t as good as I thought it would be
Mahmuda Islam –
Very much effective
In a word, awesome. Really effective for pain,sleep and cold too. And I am really happy that they have option of international shipping. I sent it to korea to my husband, he loves it.Worth it. Smell,tastes ok.
Sandra Engel –
It’s working for us!
My wife is using the PM one for her cough and cold. She’s been sleeping 100% better and the Daytime for just breathing better!